Propóleos interfiere con el ciclo celular en células de cáncer de mama
DOI:
https://doi.org/10.36790/epistemus.v19i38.424Palabras clave:
propóleos, cáncer de mama, ciclo celularResumen
El cáncer de mama es el cáncer más común en las mujeres de México y en el mundo. Múltiples investigaciones se han centrado en buscar nuevas alternativas para el tratamiento de esta neoplasia, incluyendo el estudio de productos naturales. El propóleos, una resina elaborada por las abejas, tiene una composición química muy variada, que depende de las fuentes botánicas disponibles en la zona geográfica y estación del año de recolección. Su acción antiproliferativa se debe principalmente a la inducción de apoptosis y arresto del ciclo celular. Este artículo ofrece una visión general del cáncer de mama y sus clasificaciones, examina la importancia del ciclo celular y sus diferentes fases, y aborda la complejidad química del propóleos y su actividad biológica. Por último, detalla los mecanismos intracelulares responsables del efecto antiproliferativo del propóleos en el cáncer de mama, con particular énfasis en su capacidad para detener el ciclo celular.
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